Visualized spread of neural activity

Optically visualized spread of neural activity of area CA1 of rat hippocampal slice preparation evoked by an electrical stimulation. The signal represents the change in fluorescence of voltage sensitive dye (about 5 x 10^-3 deltaF/F at the peak of the response) being incorporated into membranes of neural tissue. Frame rate is 0.7 ms/frame. The field of view is about 2 mm x 1.3 mm.

Takashi Tominaga, Ph.D.
Lab. for Brain-Operative Devices, RIKEN BSI